The main causes of HPV51 infection in women are the following: first, sexual transmission, is the most important way of HPV virus transmission, whether male infection or female infection, sexual intercourse may be transmitted to sexual partners, when suffering from viral infection try not to have sex, if sex can choose to use condoms, can block the transmission. Secondly, when the patient’s body resistance is low or when using immunosuppressants the vaginal resistance decreases and it is easy to be infected with HPV51 virus. Third, indirect contact transmission, such as close contact with patients who have HPV51 virus infection or common use of the toilet, bathroom, etc., can also be transmitted, women should pay attention to hygiene, avoid high-risk sex.