Malignant brain tumors are also known as “brain cancer”. Since the outline of the cranial cavity is full of bones, if a brain tumor grows, the pressure inside the cranial cavity will increase, resulting in headache, vomiting, blurred vision, cramps, coma and so on. In addition, the brain tumor will gradually increase in size and press on the nerves in the area, affecting its function. The location of the tumor may vary depending on the location of the tumor, including the brain cells (neurons, glial cells, lymphatic tissue, and blood vessels), nerves (Schwann cells), meninges, skull, pituitary gland, and metastatic brain tumors that have metastasized from other organs. Of course, benign brain tumors are relatively simple to treat and can be treated by resection surgery. However, for advanced brain tumors, the location of onset is special, the neurological systems in the brain will be affected and the activities will be restricted. Therefore, when it comes to the treatment of advanced brain tumor, the most important concern of many doctors is whether there is still hope for treatment and how long the patient can live after treatment. Among the treatment methods adopted, the main ones include craniotomy, radiotherapy and chemotherapy. However, many families give up active surgical treatment because the tumor is too large or around the important central nerve, and turn to the long radiotherapy and chemotherapy. In the end, the patient’s hair falls out, teeth loosen, bones are in severe pain, and he slowly passes away in pain. Is there a better way? Air Force General Hospital, under the leadership of Vice President Gu Jianwen, an expert in neurosurgery, addresses the condition of advanced tumor surgery being traumatic and losing the chance of follow-up treatment. Drawing on the theory of annihilation warfare in warfare, an asymmetric tactic and many different ways of combat are used. The idea of annihilation warfare that does not take the capture of a city and land as the only goal, but the annihilation of the enemy’s living forces as the main purpose. Concentrate on one point, the battle must seek annihilation, no matter how many ways to come, only the characteristics of the way to go, to achieve each breakthrough. According to this way of fighting with speed and efficiency, the neurosurgery team adopts the method of attacking with silver needles, multi-pronged approach, besieging and annihilating advanced brain tumors, relying on years of rich experience in stereotactic surgery, applying first-class stereotactic surgical equipment to palliatively reduce brain tumors, with multiple methods going hand in hand, following the mainstream trend of multidisciplinary collaborative treatment in the international medical field. We have achieved good treatment results. The neurosurgery department conducts a case discussion for each brain tumor patient, which is jointly completed by the neurosurgeon, gamma knife radiotherapy center, pathology department and imaging doctors. The symposium, through multidisciplinary participation, develops the best treatment plan for the patient, and also deepens the understanding of various types of brain tumors by doctors from different disciplines. According to research the most common brain tumor is glioma, which originates from glial cells, which are the supporting tissue in brain tissue. This is followed by non-gliomas, such as medulloblastoma, ventriculoblastoma, primitive neuroectodermal tumors, and atypical teratoid rhabdomyosarcoma. Patient symptoms depend mainly on two factors: the size (volume) of the tumor, and the location of the tumor. The timing and course of symptoms are usually related to the nature of the tumor (benign – slow growth/ late onset of symptoms, or malignant – rapid growth/ early onset of symptoms). The hospital’s neurosurgery expert group, Professor Yongan Huang, has provided high-quality medical care for patients with brain metastases and gliomas using stereotactic minimally invasive techniques. more than 60 cases of brain metastases and 50 cases of gliomas have been treated with satisfactory results. Technology I. Image interpretation is important for surgical decision making: Professor Cheng Gangge, Director of Neurosurgery, said that with the advancement of science, imaging examination can quickly increase the accuracy of brain tumor diagnosis and is also quite helpful for postoperative follow-up treatment. Current imaging tests include Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Electroncephalography (EEG), and cerebral angiography. Technology 2: Silver needle attack, multi-pronged approach to siege: Vice President Gu Jianwen talked about the technology, for some deeper advanced brain tumors or tumors that cannot be removed by traditional open surgery, through stereotactic technology, the nature of the tumor can be clarified and the tumor cyst fluid can be punctured and aspirated, and the patient’s symptoms in the deep brainstem, hypothalamus and motor area can be substantially linked. The multi-tube approach, on the other hand, uses this probe to implant a special Omaya drug delivery capsule to inject tumor-killing chemotherapy drugs especially through the targeted implantation of the drug chip Gliadel, which allows the slow release of drugs for continuous chemotherapy. The chip will slowly disintegrate and melt within 2-3 weeks, releasing the drug directly into the tumor area, killing those tumor cells that were not removed cleanly during surgery, and slowing down the progression of the disease by enabling the lesion to reach an effective blood concentration locally without damaging other tissues. In addition, corrosive and inactivating agents can be injected. Technology three, stereotactic radiosurgery to help: Professor Huang Yongan said about radiation therapy, radiation therapy is the use of radiation or gamma rays, high-speed neutron rays to kill tumor cells, referred to as radiotherapy. The main use of tumor cells are more sensitive to radiation and vulnerable to radiation to kill tumor cells. Generally, the treatment takes about four to eight weeks, and the size and dose of irradiation will be decided according to different tumor pathological diagnosis, differentiation degree and imaging medical examination results. Radiation therapy is an effective method for many malignant tumors and deep-seated benign tumors that cannot be safely removed. At present, radiation therapy has been developed to follow the shape or positioning methods, including linear gas pedal radiation therapy, gamma ray stereotactic radiosurgery, photon knife, etc. Technology 4, immunotherapy plus physical and psychological rehabilitation is crucial: Dr. Yan Zhou, who specializes in directional surgery, has a special understanding that although advances in imaging have enabled physicians to diagnose brain lesions by imaging, some cases require biopsy to determine the pathological diagnosis, especially when the brain tumor is evaluated to be inoperable, biopsy can help with follow-up treatment, and stereotactic biopsy is more minimally invasive. Stereotactic biopsy is more minimally invasive. Biological missiles can be used depending on the nature of the section. Immunotherapy based on the injection of DC cells and CIK cells, the patient’s own body anti-cancer cells are collected through a special blood separator and sent to a GMP clean laboratory for in vitro culture to enhance the number and function of the patient’s immune cells. After obtaining the mature DC cells with tumor recognition ability and the CIK cells with 15 billion value-added quantity and more activity and killing power, the two cells are infused back into the patient’s body and injected into the tumor cavity through the Omaya capsule to kill the tumor cells thoroughly and precisely. The family members smiled with satisfaction as they watched each patient obtain a good quality of survival under the multi-pronged approach to treatment. How to treat a patient with advanced brain tumor, Vice President Gu believes that the patient should be regarded as a “healthy person” fighting against brain tumor. We should use a holistic concept to help him/her survive with the tumor, and eventually race against the disease for the longest time. To win health and life. Therefore, it is important to choose the treatment carefully according to the severity of the disease and the degree of deterioration, and the right psychological treatment combined with physical exercise can significantly increase the possibility of curing the disease and prolong the survival period. Many times have proved that advanced brain tumor is not a terminal disease, but still has the possibility of prolonged life and long-term healthy survival.