Antihypertensive drugs that do not affect the heart rate include diuretics, angiotensin-converting enzyme inhibitors, alpha-blockers and other drugs. 1. Diuretics: diuretic drugs mainly include hydrochlorothiazide and indapamide. The main purpose is to increase urine to reduce the amount of circulating blood, reduce the preload of the heart, so as to achieve the role of assisting in reducing blood pressure, the effect on the heart rate is less obvious. 2. Angiotensin-converting enzyme inhibitors: The main representative drugs of angiotensin-converting enzyme inhibitors are Benadryl, Fosinopril and other drugs. During the use of drugs can promote the activator of adrenocortical aldosterone release, but also promote vasodilation to play a role in lowering blood pressure, and will not affect the heart function. 3. α-blockers: α-blockers are usually drugs such as prazosin and terazosin. After using the drug can antagonize the effect of α-receptor agitation, block neurotransmission, inhibit α-receptor agitation and binding, to achieve the effect of lowering blood pressure, and will not affect the heart rate. Antihypertensive drugs need to be used under the guidance of a professional doctor, combined with the degree of high blood pressure, to determine the dosage of the drug, not.