Apical inflammation can take drugs such as amoxicillin and metronidazole, but the drugs are only adjunctive treatment, and root treatment requires root canal treatment in the stomatology department. Root tip inflammation is mostly stimulated by caries or other physical and chemical factors, resulting in pulp necrosis, pus can not be drained from the tooth defect to reach the apical area, resulting in inflammation of the tissues in the apical area. The presence of a variety of bacteria and anaerobic bacteria in the oral cavity, generally use a broad-spectrum antibiotics and anti-anaerobic drugs combined medication, such as amoxicillin and metronidazole and other drugs, pay attention to the drinking period to avoid the use of drugs, allergy is prohibited to be used under the guidance of a physician, to avoid the use of private medication . Periapical inflammation according to also need to go to the stomatology department for root canal treatment, completely remove the infected material in the root canal, and the use of drugs to tightly seal the root canal, to avoid reoccurrence of inflammation.