After taking the wrinkle removal injection, it usually lasts about half a year, but due to individual differences, the specific maintenance time cannot be generalized. Wrinkle injection refers to the use of different materials (botulinum toxin, hyaluronic acid, autologous fat, etc.), injected into the local skin, which helps to relax the muscles, activate collagen, and achieve the effect of removing wrinkles. Usually, after the wrinkle injection can usually last about half a year. The maintenance effect may be shorter due to different personal constitution, or improper post-operative care, such as traveling without sun protection, improper skin maintenance, and staying up late for a long period of time, which may result in the regeneration of skin wrinkles and affect the effect of removing wrinkles. Therefore, it is impossible to generalize how long it can be maintained after taking wrinkle removing injections. For people who need to take wrinkle injections, it is recommended to go to a regular hospital to consult a doctor and clarify the relevant matters.