Interferon therapy cannot be stopped at any time. Our guidelines state that the course of treatment for both regular interferon and polyethylene glycol interferon is 1 year. Especially alpha-interferon plays an important role in the treatment of hepatitis B. Arbitrary discontinuation is not recommended and may lead to treatment failure. The use of interferon will cause some side effects, such as fever, chills, sweating, vomiting, nausea, etc. If the symptoms are mild, you can continue the treatment and drink more water appropriately, and the symptoms usually disappear within ten days, while the symptoms are severe, you need to use antipyretic and analgesic drugs and so on. However, if serious mental symptoms or other side effects occur, you need to stop using interferon and choose other drugs. It is recommended to use interferon and stop interferon under the guidance of a doctor. Drugs need to be used under the guidance of a professional physician, not to be used arbitrarily on their own.