Parkinson’s disease, also known as tremor paralysis, is a common neurodegenerative disease and the most common extrapyramidal disease in middle-aged and elderly people.The prevalence of the disease in people over 65 years old is 1,000/100,000, and it increases with age, with males being slightly more common than females. The main clinical features of the disease are: resting tremor, slowed and reduced movements, increased muscle tone, and postural instability. What are the dangers of Parkinson’s disease? 1, the gradual loss of body movement function: Parkinson’s patients usually start with a unilateral onset of symptoms, and then gradually spread to the opposite limb, the effectiveness of the treatment of the drug is gradually reduced, the side effects are becoming more and more obvious. The side effects become more and more obvious. In the middle and late stages of the disease, swallowing and vocalization will be affected, and it will be difficult to turn over at night, and insomnia will occur. Serious patients will be bedridden due to muscle contracture and joint ankylosis in the late stage. 2, closed mind, away from society: Parkinson’s patients due to limb tremor, action inconvenience, afraid of coworkers or friends laugh, unconsciously closed themselves up, away from the original familiar life, work circle. Stay at home all day. In this way, the disease is progressing, the symptoms are aggravating, the mood has become unusually bad, many patients have different degrees of depression, anxiety symptoms. 3, the family burden gradually increased: Parkinson’s disease harm will be aggravated with the aggravation of Parkinson’s patients, Parkinson’s patients families will face more and more heavy human and economic burden, Parkinson’s patients from the beginning of the occasional need to take care of people gradually to the need for one or even two specialized people to take care of the patient’s basic life. 4, triggering a variety of complications: Parkinson’s patients will be aggravated with the condition, until the late stage becomes bedridden, so there will be a decline in the function of multiple organs, the ability to fight disease is reduced, a variety of complications can occur. Among them, infections of the respiratory system are the most common, and aspiration pneumonia and crashing pneumonia can occur. Urinary infections can also become intractable and frequent due to dysuria or indwelling catheters. In severe cases, the patient’s respirator is stiff and weak, and breathing is difficult, even life-threatening. 5, other hazards: patients with Parkinson’s, the patient’s skin can be poorly conditioned bedsores, local wound infection is also a common cause of fever, and can even cause sepsis. Fever occurs in patients with advanced disease, and its treatment effect is often poor, and even endanger the patient’s life. For most patients with Parkinson’s disease, levodopa treatment is effective in the early stage of disease onset, with significant improvement in symptoms after taking the drug, and this period lasts for about 4-5 years, during which surgical treatment is not yet required. As the disease progresses and the dose of the drug increases, motor complications gradually appear, and the impact on the quality of life gradually worsens. At this time, it is necessary to seek treatment other than drugs, i.e. surgical treatment. At present, deep brain electrical stimulation (brain pacemaker, DBS) and deep brain nucleus pulposus disruption are mainly used at home and abroad.