The generic name of the drug for Herceptin is trastuzumab and the generic name of the drug for Paget is patuximab. The side effects of trastuzumab, a targeted drug for breast cancer patients, are mainly gastrointestinal side effects such as cardiac damage diarrhea and neurotoxic side effects. The side effects of Patuzumab mainly lie in granulocyte deficiency, alopecia and gastrointestinal and neurological side effects.
The targeted breast cancer drugs trastuzumab and patuzumab are both for patients with overexpression of the Her-2 gene. They are indicated for patients with Her-2 gene-positive breast cancer of any stage. One of the main side effects of trastuzumab is cardiac damage, which can cause a decrease in myocardial ejection fraction, so regular cardiac ultrasounds are needed during the medication.
The targeted drug patulizumab can mainly cause the side effect of granulocyte deficiency. In some cases, hair loss side effects can occur.
Gastrointestinal side effects and neurological side effects are generally seen with both targeted drugs, and symptomatic treatment can be given.