Most rheumatic diseases are related to autoimmune reactions, including genetic and non-genetic factors.
1. Genetic factors: when patients suffer from rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus and so on with obvious genetic susceptibility, the prevalence of patients with family history is higher than the general population.
2. Non-genetic factors: If microbial infection occurs, especially group A group B hemolytic streptococcal infection, it is the basis of causing rheumatic fever.
When the function of B lymphocytes, T lymphocytes, antigen-presenting cells and other functional immune cells is changed, it will lead to the cross-reaction of antibodies, which will lead to the continuous aggravation of inflammation of joints, skin and mucous membranes, connective tissues, etc. It is recommended that patients should be treated in a regular hospital in time.
It is recommended that patients go to a regular hospital in time, under the guidance of the doctor for examination, according to the specific results of the examination, to take targeted treatment.