Scattered white spots in the esophagus have the possibility of self-healing, but with the progression of the disease, malignant changes may also occur, and it is recommended to consult a doctor in time and intervene as early as possible. Scattered white spots in esophagus refers to the squamous epithelial hyperplasia in the esophageal mucosa, which is caused by excessive keratinization of the mucosa, and is most common in men over 40 years old, usually without obvious self-conscious symptoms. It is usually associated with long-term spicy food consumption, overheating and overcooling diet, and long-term smoking and drinking. Remove the triggers, such as quitting smoking and drinking or correcting bad dietary habits, there is a certain degree of self-healing possible. However, if the scattered white spots in the esophagus keep spreading and have a larger scope, and the white spots are higher than the normal mucous membrane, there is a possibility of cancer, and histological biopsy is needed to exclude the possibility of malignancy. Although the scattered white spots in esophagus may be cured by themselves, they may develop into malignant lesions as the condition progresses. It is recommended to consult a doctor in time and intervene as early as possible under the guidance of a professional physician to avoid delaying the condition.