Urine protein can be checked in the afternoon if it is checked by means of urine routine; if it is checked by 24-hour urine protein quantification, it is better to start from the morning. Urine protein is mainly caused by the destruction of glomerular filtration barrier and tubular epithelial cell damage causing protein in urine. When there is a problem with the kidneys, you can check whether there are abnormal changes such as protein and red blood cells through routine urine examination, and the examination is not limited by time, so you can check it in the afternoon. When a routine urine test is positive for protein in the urine, the protein loss can be assessed in detail by checking the 24-hour urine protein quantification. This test needs to be done by collecting is by collecting all the urine for 24 hours to determine the amount of protein in it. Starting in the afternoon may affect the accuracy of the result, it is better to start collecting and testing from the morning. If you find abnormal urine protein, please consult the hospital in time, choose the appropriate test under the guidance of the doctor, and actively diagnosis and treatment to avoid delaying the condition.