Severe itchy skin on the feet and legs could be hives, neurodermatitis, eczema, or a fungal infection. It is treated by topical medication and oral medication. 1. Hives. Related to allergy, infection factors. Manifested as edematous windswept masses with itching. It can be treated with oral antihistamine drugs, such as ebastine, diclofenac tadalafil, and topical glycerine lotion. 2. Neurodermatitis. Manifested as thickening of the skin, mossy changes, can be localized topical antihistamine ointment, such as cyproheptadine cream, chlorcyclizine hydrochloride cream and so on. Topical halometasone cream and other glucocorticoid creams to minimize local irritation. 3. Eczema. Manifested as erythema, papules, accompanied by itching. You can take oral antihistamines, such as ebastine, diclofenac tadalafil, local topical mometasone furoate cream and other glucocorticoid cream. 4. Skin fungal infection. Manifestation of skin erythema, blisters, flaking. Topical antifungal medication ointment, such as terbinafine cream, miconazole nitrate cream and so on. The drugs mentioned above need to be used under the guidance of a doctor, and itchy skin on the feet and legs can be serious to the hospital dermatology department.