Two-hour postprandial blood glucose 19.1mmol / L may be acute infections and other stressful situations, diabetes, diabetic ketoacidosis and other factors caused by the need for targeted treatment under the guidance of the doctor, such as general treatment, drug therapy, and so on. 1. Acute infections and other stressful situations: for example, acute pancreatitis may appear in the case of elevated blood glucose, fasting, gastrointestinal decompression treatment, combined with infections can be treated with antibiotics, such as metronidazole; concomitant perforation, obstruction, etc. need to consider surgical treatment. 2. Diabetes mellitus: diabetes mellitus caused by two-hour postprandial blood glucose elevation can be considered using metformin, acarbose and other hypoglycemic drugs, or insulin injection treatment, with dietary control, appropriate exercise. 3. Diabetic ketoacidosis: immediate rehydration therapy is needed, followed by small-dose insulin drip treatment, potassium supplementation is necessary to avoid the occurrence of hypokalemia. When two-hour postprandial blood glucose of 19.1mmol/L occurs, it is recommended to go to the hospital and ask the doctor to make judgment and give treatment plan.