In clinical practice, the use of mifepristone for a short period of time is mainly indicated for the conservative treatment of medication abortion and ectopic pregnancy. It is normal that patients do not respond to mifepristone for 2 days, because mifepristone is only a progestin antagonist, which antagonizes progesterone and causes the embryo to lose progesterone support and die. During the first 2 days of the drug, the embryo is in a gradual death process. At this time, the patient does not experience contractions of the uterus, so there is no abdominal pain or vaginal bleeding. Usually, abdominal pain and vaginal bleeding will occur only when misoprostol is taken on the third day of the medication abortion. Patients with ectopic pregnancy usually need to take mifepristone for 3-4 days with the addition of methotrexate, and in most cases the patient has no clinical symptoms or presents with only a small amount of vaginal bleeding. Because patients with ectopic pregnancy do not use drugs that promote uterine contraction for fear of causing rupture of the ectopic mass, the effect of the drugs is mainly judged by checking the change of blood HCG.