Dissecting the major problems of asthma

        Definition of asthma: It is a chronic inflammatory disease of the airways involving multiple cells, including inflammatory and structural cells of the airways (e.g., eosinophils, mast cells, T lymphocytes, neutrophils, smooth muscle cells, airway epithelial cells, etc.) and cellular components.  Chronic inflammation leads to airway hyperresponsiveness, usually with widespread and variable reversible airflow limitation, and causes recurrent episodes of wheezing, shortness of breath, chest tightness or coughing, which often flare up and worsen at night and/or early in the morning. Most patients experience spontaneous relief or relief with treatment.  Treatment goals for asthma: No (or <2/week) daytime symptoms No daily activities, including limited exercise No nocturnal symptoms or awakening due to asthma No acute exacerbation of asthma (defined as asthma requiring oral hormone therapy, or emergency or hospitalization) No (or <2/week) requiring treatment with relieving medications What are the routine ancillary tests for bronchial asthma?  - Common pulmonary ventilation function measurements for asthma - Bronchodilator test or provocation test - PEF variability - Sputum eosinophil count - Exhaled breath NO assay - Allergen skin test and serum specific IgE assay.