The indications for sodium vitrate injection are mainly osteoarthritis of the knee joint. The main effect is to promote the repair of damaged cartilage and to facilitate the secretion of synovial fluid from the cartilage, thus reducing the symptoms. This drug is injected once a week for 3-5 weeks to provide good relief. When injecting this drug, make sure to sterilize it to prevent infection of the knee joint. It is important to take rest and avoid strenuous exercise, especially hiking, climbing stairs, etc. Oral anti-inflammatory and analgesic drugs, such as loxoprofen sodium, can be used, as well as drugs that nourish cartilage, glucosamine hydrochloride and chondroitin sulfate can be used together. When performing sodium vitaminate injection knee puncture injection, anti-inflammatory short-term hormone injection, such as tretinoin injection, can be injected. It is still important to keep warm and avoid getting cold, and pushing and massage are generally not recommended. If osteoarthritis of the knee joint cannot be effectively relieved by this treatment, arthroscopic minimally invasive surgery can be considered.