An intact skull plays a major role in contouring and maintaining the normal functioning of brain tissue. However, in today’s society, there are frequent traffic safety accidents and production safety accidents, coupled with cranio-cerebral surgery, all of which are likely to disrupt the integrity of the skull, resulting in one or more defects. There are many latent dangers associated with long-term cranial defects. The collapse or bulging of the top of the head in most patients with cranial defects not only affects aesthetics, but may also cause brain bulging, herniation of the brain, cerebral atrophy, hydrocephalus, and other more serious conditions. It can also cause cranial defect syndrome such as headache, vertigo, irritability, discomfort that can not be explained by other reasons and various mental disorders. Therefore, timely cranial bone repair has become an urgent and important issue. Of course, the cranial bone repair material is also very important, clinical application of titanium mesh can meet the needs of most patients, but it is easy to be exposed after surgery, deformation, and rejection reaction. The new biomaterial polyether ether ketone peek material, which was widely used in Europe and the United States at an early stage, has proved to have good performance in terms of histocompatibility, shaping, hardness, and imaging, which greatly reduces surgical failures as well as complications. Especially important is that patients can personalize the peek plate according to their own situation, restore the shape of the skull, so that the skull repair to a perfect state. Therefore, repairing the skull suggests that patients choose peek material, and currently peek material has become the new trend of cranial bone repair material. In order to help the majority of domestic patients with cranial defects early recovery, we introduced advanced peek material and optimization of design, while in the surgical aspects of the idea of aesthetic plastic surgery deliberately added to the technology upgraded to peek cranioplasty. peek cranioplasty in the three-dimensional reconstruction based on the realization of the preoperative virtual reconstruction, to achieve the structural restoration, functional perfection, the appearance of the external appearance of the overall unity.