The late stage of AIDS is generally the period of AIDS onset, which may take from 2 to more than 10 years. The late stage of AIDS is generally the AIDS onset stage. The number of CD4+ cells in the body of these patients is greatly reduced, and they will develop fever, swelling of lymph nodes, weight loss, headache and other related symptoms, and various opportunistic infections and tumors due to impaired immunity of the body. It takes an average of about 2 to more than 10 years for AIDS to develop into this period. The time for AIDS to develop to the late stage varies from person to person. Some people with poor immunity and active HIV replication may have a shorter time, while patients with a better basic state, less active viral replication, and active antiretroviral treatment will develop more slowly, and may not even reach the late stage of AIDS. Some patients may also have symptoms related to the early stage of AIDS, but generally the symptoms are relatively mild, the late stage of AIDS will appear lymphocyte destruction, patients will also be combined with malignant tumors, serious infections, may endanger the patient’s life. Therefore, AIDS should be treated as soon as possible, and follow the doctor’s instructions to take medication, once the development of advanced stages, the treatment prognosis is poor, and the mortality rate is high.