Lymph node hypoechoicity is a description of lymph node abnormality on ultrasound, which can occur in a wide variety of conditions and can be considered as a result of inflammatory response, neoplastic disease, or hematologic disorders, but it is important to use a combination of these in conjunction with the normalization of blood flow through the lymphatic gate. It should be noted that ultrasonography is only a preliminary screening for lymph node lesions, and usually other tests are still needed to make a comprehensive judgment or biopsy under ultrasonography to determine. 1. Inflammatory reaction: when lymph nodes are inflamed, it will cause lymph node inflammatory reaction hyperplasia, resulting in lymph node hypoechoicity. For example, pharyngitis and other head and face infections can cause cervical lymph node enlargement. Usually, after the cause of the disease is clarified, the infection can be controlled actively, and usually can be improved. 2. Tumor: some tumors develop lymph node metastasis, which can cause lymph node hypoechoicity, such as breast cancer causing axillary lymph node metastasis, resulting in axillary lymph node hypoechoicity. 3. Hematologic diseases: In some cases of lymph node hypoechoicity, if other causes of lymph node enlargement cannot be clearly found, then one should consider whether there is a disease of the blood system such as lymphoma. When hyperechoic lymph nodes occur, you should go to regular hospitals for early treatment.