Sweating in the second half of the night can be attributed to physiological factors, such as high ambient temperature and overly thick blankets; it can also be attributed to pathologic factors, such as tuberculosis and other infectious diseases, hyperthyroidism, menopausal syndromes and other illnesses, and further examination is recommended. 1. When there are infectious diseases such as tuberculosis, night sweats in the second half of the night (abnormal sweating after going to sleep and stopping after waking up) can occur due to systemic toxicity caused by tuberculosis bacilli. 2. When suffering from hyperthyroidism, due to the increase of basal metabolic rate in the body, there can be body wasting, body weakness, night sweating. In addition, women with menopausal syndrome may also experience night sweats in the second half of the night and irritability due to disorders in estrogen and progesterone levels. Therefore, it is recommended to go to the hospital in time for further examination and targeted treatment after clarifying the cause of the disease.