The duration of hormones to reduce fever varies. 1. short-acting hormones, like hydrocortisone, can last about 8 hours; 2. medium-acting hormones, like prednisone, can last 12-36 hours; 3. long-acting hormones, like dexamethasone, can last more than 36 hours, up to 54 hours. Hormones to reduce fever have great risks, do not use them indiscriminately, unless it is recommended to apply hormones only when the body temperature is too high to reduce fever, for a short time to make the body temperature drop, and the dose of the best grasp. Although large doses of hormones can reduce fever, they can also easily induce diseases, such as necrosis of the femoral head and other lifelong diseases, and may even cause disability. Clinical hormone administration is best under the guidance of a physician for greater safety.