Cold, damp and swollen testicles may be caused by varicocele, prostatitis and scrotal eczema, with different causes and different medications, including MaiZhiLin, Levofloxacin and Cetirizine. For severe varicocele disease, surgery should also be considered. 1. Varicocele: When varicocele disease exists, medications such as Myzolin and Diosmin tablets can be used to control the development of the disease and alleviate the uncomfortable symptoms. When the varicocele is more serious, such as causing male infertility, surgical treatment should be carried out, such as laparoscopic high level ligation of the spermatic vein. 2. Prostatitis: When there is prostatitis, you can apply tamsulosin, levofloxacin and other drugs for treatment, and with physical therapy, such as heat therapy, microwave therapy, etc., to accelerate blood circulation, promote the absorption of inflammatory substances, is conducive to the recovery of prostatitis. 3. Scrotal eczema: When there is scrotal eczema, you can use external glycerine lotion and tacrolimus ointment to treat it, and you can also take oral cetirizine and loratadine to treat it. In the use of drugs must follow the doctor’s guidance, rational use of drugs, do not use drugs, to avoid causing serious adverse reactions.