TCT, short for liquid-based thin-layer cytometry, is commonly used to detect and cytologically categorize cervical cells, and squamous cells detected by TCT suggest the possibility of cervical inflammation or other cervical pathologies. Clinically, the analysis of the results of TCT after the detection of squamous cells also needs to be combined with HPV testing, which can improve the accuracy of cervical cancer screening. If there is HPV infection, and it is a high-risk type of HPV infection, colposcopic biopsy should be recommended at this time for further judgment, to see if cervical lesions (such as neoplasia or carcinoma) are already present, and regular review is required. The presence of atypical squamous cells is usually closely related to cervical inflammation. Therefore, when squamous cells are detected by TCT, regular review of TCT and HPV testing is needed.