High androgens may be caused by polycystic ovary syndrome, hyperadrenocorticism, and testicular hyperfunction. 1. Polycystic Ovary Syndrome: It is the most common disease causing elevated androgens. The specific cause of the disease is unknown and may be related to genetics and environment. Hyperinsulinemia can promote the synthesis and secretion of androgens by the follicles and adrenal glands. In addition, the increased activity of enzymes related to androgen synthesis in the reticular zona of the adrenal cortex also leads to the increase of androgens. 2. Hyperadrenocorticism: androgens are partly synthesized and secreted by reticular zona reticularis cells of the adrenal cortex, and the amount of synthesized and secreted androgens increases when hyperadrenocorticism occurs, resulting in high androgens. 3. Testicular hyperfunction: testicular interstitial cells can synthesize androgens, and when the testes are hyperfunctional, androgen synthesis increases. High androgens may be related to a variety of factors, and it is recommended to consult a doctor for a clear diagnosis.