The fleshy prickly buds growing at the coronal groove of the glans may be pearl rash of the penis, and it is recommended that the cause be clarified after further examination at the hospital. If it is a pearl rash of the penis, it is often distributed at the coronal groove of the glans, near the side of the foreskin tether, as soft white fleshy bud-like changes or fleshy ding-like changes. There is no discharge, no pain, local bleeding, etc., no sensation when touched, and can be long-lasting. It may be related to factors such as overcircumcision or circumcision, and is a benign lesion. There is no need for surgical treatment. If you are overly concerned, local electrocautery treatment is feasible. However, if cauliflower-like or papilla-like changes are seen, accompanied by local pain, bleeding or gradual increase in number and volume, other viral infections should be considered. If the human papillomavirus infection is caused by warts, you need to go to the hospital for further relevant examination. If the diagnosis of warts is confirmed, surgical removal and a combination of antiviral and other treatments will be required.