There are many reasons why the inner knee bone hurts when pressed, such as strain, trauma, inflammation and osteophytes. 1. Strain: excessive activity of the knee joint, localized accumulation of lactic acid and pain. 2. Trauma: The inner side of the knee joint is damaged due to external impact, resulting in meniscus injury or ligament tear and pain. 3. Inflammation: Pain due to osteoarthritis of the knee, rheumatoid arthritis, etc., resulting in lesions of the knee joint. 4. Osteomalacia: Degenerative disease caused by fibrosis of knee joint cartilage due to various factors, resulting in knee joint pain as the main cause. The lesions often involve the bone, synovium, joint capsule and other structures of the joint. There may be other causes of pain when the inner knee bone is pressed, when there is pain when the inner knee bone is pressed, you should go to the hospital at the first time, early diagnosis and early treatment.