The difference between total excision and hemisection of thyroid cancer is that the target situations are different, and the postoperative complications are also different. 1. Different situations: total excision of thyroid cancer refers to the total removal of thyroid glands on both sides, while hemi-excision only removes the thyroid gland on one side. If there is no clear family history and the preoperative imaging examination considers unilateral smaller thyroid cancer, unilateral gland and isthmus lobectomy can be performed. If it is thyroid cancer with multiple cancer foci in both lobes of the gland, or thyroid cancer that has developed distant metastasis, total thyroidectomy is needed. 2. Postoperative complications are different: after unilateral thyroidectomy, hypothyroidism usually does not occur, but if all the thyroid glands are removed bilaterally, hypothyroidism will occur, and lifelong supplementation of levothyroxine will be needed. If you are diagnosed with thyroid cancer, you should follow the doctor’s instructions for treatment, communicate with your doctor more before surgery and have the surgery according to your own situation, and have a review on time after surgery.