It is well known that cerebrovascular lesions can cause stroke and cardiovascular lesions can cause angina pectoris and even myocardial infarction. However, ischemic abdominal pain, blood in the stool and other related symptoms (ischemic gastrointestinal disease) caused by intra-abdominal vascular lesions are often not taken seriously. In fact, the pathogenesis of both is similar. Both are seen in middle-aged and elderly people, and often occur on the basis of underlying diseases such as atherosclerosis, hypertension, diabetes mellitus, coronary heart disease, and chronic constipation. It is known that the gastrointestine is an important organ for digesting food, absorbing nutrients and water, and the various activities of the gastrointestine depend on the three major branches of the abdominal aorta, namely the celiac artery, the superior mesenteric artery and the inferior mesenteric artery, to provide sufficient blood to complete. If lesions of the above-mentioned vessels lead to insufficient blood supply to the corresponding organs, it is natural to have abdominal pain, abdominal distension, nausea, vomiting, blood in stool and other symptoms. In the past, due to the lack of awareness of this disease, few people were diagnosed with this disease, but nowadays, due to the improvement of awareness of this disease and detection methods, it is not uncommon to diagnose this disease; over the years, dozens of people have been diagnosed with this disease by colonoscopy in our laboratory due to acute abdominal pain and blood in stool. Ischemic gastrointestinal disease is divided into two categories, chronic and acute, depending on the urgency of onset and the amount and speed of ischemia. Chronic cases show intermittent pain in the left upper abdomen or around the umbilicus, which starts 15 minutes or half an hour after eating and lasts 1-2 hours each time, and they are afraid to eat more or even refuse to eat because of fear of eating. After a long time, weight loss, physical strength decreases day by day, often easily mistaken for gastric ulcer or gastric cancer, although there is no evidence of ulcer or cancer by gastroscopy, some people also have symptoms such as abdominal distension, belching, nausea and vomiting. Another type of acute ischemic enteritis, sudden spasmodic pain in the lower abdomen, urgency, black stool or fresh blood stool, lesions are mostly located in the left hemicolectomy (i.e., descending colon, sigmoid colon), with significant pressure pain due to tension in the left abdominal muscle at the onset. Blood can be found in the finger sleeve during finger examination of the rectum. There is pressure pain around the rectum and shock in severe cases. Colonoscopy often has more characteristic mirror image changes. A few cases of ischemic colitis have mild abdominal pain and bleeding that persist for several days or weeks and then resolve spontaneously. Chronic ischemic gastric disease is similar to gastric ulcer, gastric cancer, functional dyspepsia and other symptoms; ischemic colitis is similar to ulcerative colitis, Crohn’s disease, colon cancer symptoms, which can easily lead to misdiagnosis, therefore, if there are related symptoms mentioned above, you should see a gastroenterologist in time. The use of modern electronic gastroscopy, abdominal angiography, etc. can better identify and diagnose. Prevention of ischemic gastrointestinal disease is important. Pay attention to diet regulation, do not overeat, and eat less food with high fat content to prevent thrombosis. Take part in physical exercise, which can dilate blood vessels, increase the elasticity of blood vessels, promote blood circulation and avoid embolism of blood vessels. Those with underlying diseases should be treated actively to prevent the problem before it occurs. In order to reduce the burden on the gastrointestinal tract during acute attack, fasting and even gastrointestinal decompression, bed rest; use vasodilators, prevent and control infection, maintain water-electrolyte balance and other supportive symptomatic treatment; perform surgery if necessary in severe cases.