The side effects of clomiphene are as follows: a. Improper use of the drug may lead to premature ovarian failure, which may be irreversible once it occurs clomiphene is used, the ovarian function must be checked and other health conditions must be checked before clomiphene is used, and a comprehensive analysis can determine whether ovulation can be promoted for treatment. Clomiphene may cause ovarian hyperstimulation in the process of use, resulting in lower abdominal distension and pain, large amount of ascites, urine and breathing difficulties, and other symptoms of ovarian hyperstimulation, which may improve on their own after rest in mild cases, but in severe cases, hospitalization is required to give appropriate treatment to achieve the purpose of cure. Clomiphene ovulation promotion often thickens the local mucus of the cervix and reduces the chance of sperm crossing the cervix, so although the success rate of ovulation promotion is relatively high, the success rate of pregnancy is relatively low.