Blood pressure measurement is the primary means of assessing blood pressure levels, diagnosing hypertension, and observing the efficacy of antihypertensive therapy. Currently, three main methods are used in clinical and population prevention and treatment: office blood pressure, ambulatory blood pressure, and home blood pressure. In-office blood pressure is measured by health care professionals in the office according to a standardized protocol and is still a common method for assessing blood pressure levels and for clinically diagnosing and grading hypertension. Ambulatory blood pressure monitoring (ABPM), on the other hand, is usually done by an automated blood pressure measurement instrument, which measures more frequently, has no measurer error, avoids the white coat effect, and measures blood pressure during sleep at night, thus allowing for both more accurate blood pressure measurement and assessment of short term blood pressure variability and circadian rhythms. Home blood pressure monitoring (HBPM) is usually done by the person being measured, which is then also referred to as self-testing or home-based blood pressure measurement, but can also be done with the assistance of family members and others. Because the measurement is performed in a familiar home environment, thus, the white coat effect can also be avoided. Home blood pressure monitoring can also be used to assess the long-term variability of blood pressure or the effect of antihypertensive therapy over days, weeks, or even months and years, and it can help to increase patient awareness of participation and improve patient compliance with therapy. In-office blood pressure is more achievable compared to ambulatory blood pressure and easier to control quality compared to home blood pressure, and therefore remains the primary method for assessing blood pressure levels today. However, if 24-hour ambulatory blood pressure monitoring is available, 24-hour ambulatory blood pressure can be used as a basis for consultation and treatment.