The skin on the feet falls off layer by layer, which can be considered to be related to tinea pedis, exfoliative keratolysis or palmoplantar pustulosis and other diseases. 1. Tinea pedis: it can be infected by sharing shoes, socks and foot basin with tinea pedis patients, such as impregnated tinea pedis, the skin in the crevice of the finger is white due to sweating, water immersion, etc., and the epidermis is soft and easy to peel off, which can reveal the surface of the vesicles or oozing liquid. 2. Exfoliative keratolysis: it may be related to emotion, nervousness or hyperhidrosis, etc. It may appear on the soles or even the backs of the feet, with scales and white dots at the beginning, which can be gradually enlarged like dried blisters, and can be easily torn to become paper-thin scales. 3. Palmoplantar pustulosis: the etiology is unknown, may be related to local infections, metal allergies, heredity, stress, and smoking, drugs, etc., often manifested as the first blisters occurring on the soles of the feet or palms of the hands in the center of the blisters, which rapidly become pustules, scabs dry, peeling, pustules can be fused, can be spread. Frequent peeling of the skin on the feet, can go to the hospital specialist consultation, follow the doctor’s instructions standardized medication.