The causes of large follicles that do not ovulate are as follows: 1. endocrine disorders may occur in women, such as low levels of luteinizing hormone, which can prevent the follicles from being discharged normally. 2. when women suffer from excessive psychological stress and abnormal mood swings, which can cause abnormal secretion of lactogen, this can also cause ovulation. 3. inflammation of the reproductive organs in women, when women suffer from ovarian When women suffer from inflammation of the ovaries and ovarian adhesions, it can also cause the follicles to develop too large and not be able to discharge on their own. When a woman has large follicles that do not expel themselves, she should be careful to stay relaxed, have a regular lifestyle, and actively treat ovarian inflammation. If this is due to hormonal disorders, luteinizing hormone levels can be increased or clomiphene can be given to promote the normal discharge of mature follicles.