The right lobe of the liver substantial medium strong echogenic nodule consider the possibility of hepatic bile duct stones, intrahepatic calcification foci, hepatic hemangioma, hepatocellular adenoma, and so on. 1. Hepatic bile duct stones: ultrasound can see strong echogenic masses in the hepatic bile ducts, with acoustic shadows behind them, often multiple, distributed along the bile ducts, most of them are caused by diet, infection and other factors, and the main manifestations are pain in the right epigastric abdomen, high fever, jaundice, and the pain can be radiated to the back of the right shoulder. 2. Intrahepatic calcified foci: right lobe of the liver is common, ultrasonography is preferred, it can be seen as a strongly echogenic lesion of the liver parenchyma, which is isolated and can be accompanied by acoustic shadows in the posterior. It can be caused by stones, tumors and parasitic diseases, and other liver lesions should be excluded. No treatment is needed after definite diagnosis, and regular follow-up is enough. 3. Hepatic hemangioma: ultrasound shows that it is often seen as a hyperechoic parenchymal mass in the liver, with uniform distribution of internal echoes and clear boundary. 4. Hepatocellular adenoma: ultrasound can see a clearly defined echogenic area with uneven distribution of internal echoes, within which stronger echogenic spots can be seen. The right lobe of the liver may also have other causes, such as malignant tumors of the liver. It is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy.