Left shoulder pain at the age of 53 may be a manifestation of frozen shoulder, or it may be caused by rotator cuff injury, cervical spondylosis, or visceral diseases. Frozen shoulder refers to the joint capsule, ligaments and other soft tissues around the shoulder joint, due to degeneration, strain and other causes of aseptic inflammation, which can cause shoulder pain and shoulder joint activity limitation and other symptoms, and is more likely to occur in the middle-aged and elderly people around the age of 50, therefore, 53-year-old left shoulder pain may be suffering from frozen shoulder. However, many causes can cause left shoulder pain, such as rotator cuff injury, neurogenic cervical spondylosis, and internal diseases such as coronary heart disease and aortic coarctation, which can also cause left shoulder pain. When left shoulder pain persists without relief, it is recommended to go to the hospital for further consultation, complete the relevant examinations, clarify the cause of the disease and then follow the doctor’s instructions for targeted treatment, so as to avoid delaying the condition.