Niu Huang Pills usually refers to Angong Niu Huang Pills, which are not recommended to be taken after ten years of expiration. Angong Niuhuang Pills is a kind of Chinese patent medicine, which is composed of in vitro cultivated cow’s rhubarb, artificial musk, pearl, vermilion, andrographis, yellow rhubarb as well as ice tablets and other herbs, and is suitable for stroke coma and encephalitis, meningitis, toxic encephalopathy, cerebral hemorrhage, sepsis and other disorders. There is no clear adverse reaction, but it is forbidden for people who are allergic to the ingredients of the drug, and pregnant women and athletes should be careful. After the expiration of the drug, the composition of the drug may change, and the efficacy of the drug will be reduced, or disappear, taking and can not treat the disease, and may even cause harm to the body. Therefore, ten years after the expiration date of Angong Niuhuangwan is not recommended to eat. When taking medication, you should follow the doctor’s instructions, not to take, stop, change medication.