Is it normal to have abdominal discomfort even after 12 days on the quadruple pill?

Taking quadruple drugs 12 days abdominal still uncomfortable, may be the drug produced by the gastrointestinal discomfort reaction, after stopping the drug can disappear, but also may be caused by physiological factors.
Eat quadruple drugs for 12 days, the purpose is to remove the Helicobacter pylori, some patients can still appear abdominal discomfort, generally normal.
Metronidazole and clarithromycin in the quadruple medication have obvious stimulation of the gastrointestinal tract, for example, metronidazole has the most common gastrointestinal reactions, including nausea, vomiting, loss of appetite, abdominal cramps, which generally do not affect the treatment. Clarithromycin can also be seen nausea, heartburn, abdominal pain and diarrhea, temporary transaminase elevation, etc., can be recovered after stopping the drug.
Eat four drugs 12 days abdomen is still uncomfortable, may also be high oil, high protein diet caused by physiological discomfort, usually after digestion of food can disappear.
The abdomen is still uncomfortable for 12 days after taking the quadruple pill, it is recommended to consult a doctor in time to find out the cause and treat the cause of the problem, and the above medication is in accordance with the doctor’s instructions.