Patients with pediatric anaphylaxis syndrome have persistent cyanosis from birth. Difficulty in breathing. Feeding difficulties. Growth retardation. Tachycardia with signs of hypoxia. It resembles cyanotic congenital heart disease. Spleenless syndrome, also known as Ivemark syndrome, spleenless with congenital heart disease syndrome, splenic insufficiency syndrome, congenital splenic agenesis with atrioventricular and visceral transposition syndrome, etc., is characterized by congenital splenic insufficiency or absence of spleen, with cardiac macrovascular malformation with cavernous and pulmonary venous reflux anomalies, and combined with abnormal position of thoracoabdominal viscera. So what are the screening methods for persistent cyanosis right after birth? The following is an explanation for you. 1, persistent cyanosis: the patient has persistent cyanosis after birth, breathing difficulties, feeding difficulties, growth retardation, tachycardia and presents symptoms of hypoxia, cool cyanotic congenital heart disease. 2, signs and symptoms of cardiovascular abnormalities: older patients may have pestle-like fingers (toes, elevated precordial area, and diffuse systolic murmurs along the left edge of the sternum in about half of the cases. 3, no spleen: abdominal ultrasound reveals a very small or even absent spleen. 4. Poor immune function: low resistance. Various infections often occur. Severe infections are often the cause of death. 5.Multiple malformations: In addition to the absence of spleen and cardiovascular malformations. There are often abnormalities such as gastrointestinal transposition. 6, cyanosis: cyanosis persists after birth. 7, digestive system: internal organs transposition, left and right symmetrical liver in transverse hepatic, spleen absent or very small, splenic artery absent. 8.Cardiovascular system: residual superior vena cava on both sides, parallel inferior vena cava and descending aorta. 9.Blood examination: the presence of Howell-Jolly vesicles in peripheral blood erythrocytes is of confirmatory significance.