Acute otitis media effusion, mostly referred to as fluid in the tympanic cavity of acute secretory otitis media, usually cannot be cured on its own, and should be standardized under the guidance of a doctor. This disease is usually caused by upper respiratory tract infection when one’s own resistance drops. After the occurrence of middle ear cavity effusion, hearing loss, earache, low-pitched intermittent tinnitus, occlusion or stuffy feeling in the ear and other symptoms may occur, which need to be treated with antibiotics such as cephalexin, cefuroxime and other antibiotic treatments under the guidance of a doctor, and at the same time, short-term glucocorticosteroid therapy is used. When acute otitis media effusion occurs, it is recommended to actively seek medical attention to clarify the etiology and extent of the condition, and follow the doctor’s instructions to standardize medication and treatment to avoid complications such as adhesive otitis media, tympanic chamber sclerosis, cholesterol granuloma and acquired primary cholesteatoma.