After bone metastasis occurs in lung adenocarcinoma, foot swelling usually does not occur, but hypoproteinemia, compression or blood clots can also cause patients to develop foot edema. Lung adenocarcinoma is one of the common pathological types of lung cancer, which is mostly caused by environment, heredity, gene mutation and other factors. With the development of the disease, patients with advanced stage may have bone metastasis and other distant metastasis. Patients may have symptoms of corresponding metastatic sites, such as bone pain, pathological fracture, localized lumps, etc. Lung cancer belongs to consumptive disease, when patients have hypoproteinemia, tumor metastasis to the pelvic area compressing lymphatic vessels or thrombus, etc., it can lead to the symptom of lower limb edema. At this time, symptomatic treatment can be carried out by taking diuretics such as furosemide, spironolactone and infusion of albumin as prescribed by doctor. Please strictly follow the doctor’s instructions for medication, and do not use medication on your own.