Breast 4c generally refers to the BI-RADS grading of breast masses, and patients with a general grade of 4c have a higher likelihood of malignancy, not always benign. According to the BI-RADS classification of breast masses into 0-6, generally 4 grade refers to the suspected malignant tumor, and is divided into 4a, 4b, 4c three categories. 4a grade patients are less likely to be malignant, 3% ~ 10%. 4b grade patients the possibility of malignancy is 10% ~ 50%, and the possibility of malignancy of patients with 4c is 50% ~ 94%. Therefore, patients with a BI-RADS classification of 4c for breast masses may not always actually be benign, but instead have a higher likelihood of malignancy. It is recommended that patients undergo a mammocentesis biopsy to clarify the exact nature of the breast mass. Once malignant lesions are diagnosed, early surgical excision is required, with some patients receiving adjuvant treatment such as radiotherapy, chemotherapy and targeted therapy. It is recommended that patients with breast nodules should consult regular hospitals in time and standardize the treatment under the guidance of doctors.