To determine whether a runny nose is a novel coronavirus infection, patients should be asked about their epidemiological history and other clinical manifestations, such as recent travel to infected areas, contact with patients who may be infected, or clusters of cases. For these high-risk groups, the occurrence of runny nose should be taken seriously, because a small number of patients with novel coronavirus infection can have runny nose symptoms, similar to a cold, and should be differentiated accordingly by early improvement of blood tests and chest CT. When suspicious viral lung formation is seen in the lungs, early detection of novel coronavirus nucleic acid in respiratory specimens should be improved to rule out any related infection. Of course, we should also focus on the presence of viral cold or allergic rhinitis when we have a runny nose all the time. Usually, we can only consider the presence of cold or rhinitis when we complete the relevant examination and exclude the epidemiological history.