The arrival of a new baby is a joyous occasion, but the situation of this family was a bit special. As soon as the baby was born, the thumb was tethered to the hand like a small meatball, unable to follow subjective activities, and could only swing with the swing of the wrist, weak, and with a total loss of thumb function. Before the baby was born, the parents and the elders of the family and the clan had not encountered this situation, and knew nothing about the disease, the whole family was in a panic …… “No one in our family has this condition, why does the baby have it?” I was just coming out of the medication change room when the pair of parents came to find me. Outside the clinic, the mom was holding the baby, the dad was dragging his luggage, and both of them looked anxious, I just pushed the door in with my front foot, and they followed with their back foot, and their mouths didn’t forget to greet me: “Professor Chen, help show my baby” I just sat down in front of the computer, and in the next second, the baby’s hand was taken to me by the mom, at the same time At the same time, the father’s explanation also sounded in time: “Our child was born like this, but no one in our family is like this, why does the child have it?” In fact, this kind of question is basically asked by parents who come to my clinic. Although it is true that there is a “genetic” factor in the development of hand deformities, it does not mean that all deformities are caused by “genetic” factors, but there are certain chances. For example, this baby has a floating thumb, which is often referred to as a bunion, and its causative factors are complex, including nutritional deficiencies, fetal neurogenic injury, maternal viral infections, the effects of medications (especially the sedative thalidomide), and hypoxia, all of which may lead to the development of a floating bunion in babies. Newlyweds take medication to suppress acne, leaving hidden dangers in preparation for pregnancy Later, after I made some inquiries, the baby’s father said a very crucial point. It turns out that when they got married, Dad had some acne on his face. In order to make the wedding ceremony more perfect and not to give himself any regrets, Dad used some medication to get rid of the acne shortly before the wedding, and did not take any other measures after the wedding, and his wife got pregnant soon afterward, so Dad was very skeptical about whether it was caused by this. Because the causative agent of floating bunions is complex, we cannot completely rule out this factor, it is possible that it may have some impact on the development of the baby, of course, if we want to be more specific to determine the cause of the disease, we need greater data and cases to study. In order to minimize the chances of the baby being born with hand deformities, we recommend that both the mother and father do a good job of preparing for pregnancy, and both try to maintain a healthy state of mind and body, and be prepared to welcome the arrival of the baby.