There are two kinds of lymph node enlargement in the liver and stomach space, one is caused by bacterial and viral infection, which can be relieved by oral medication; one is caused by benign or malignant tumors, which can be relieved by surgical resection and so on. 1. Lymph node inflammation and enlargement caused by bacterial and viral infections: such as gastric ulcer, gastritis, etc., can be treated with oral medication, and commonly used medications include omeprazole enteric-coated capsules and so on. 2. Enlargement of lymph nodes caused by benign tumors: such as liver cysts, gastric smooth muscle tumor, gastric fibroma, etc., for which surgical resection can be taken in general, and with postoperative conditioning. 3. Lymph node enlargement caused by malignant tumor or tumor metastasis: such as gastric cancer, liver cancer, lymphoma, etc. According to different conditions, early stage can be surgically resected with chemotherapy and radiotherapy with alkylating agents such as carmustine injection and anticancer medicines such as adriamycin hydrochloride, etc.; in the late stage or metastasis with no surgical indications, chemotherapy can be used together with targeted therapy and immunotherapy with medicines such as afatinib maleate. When there is enlarged lymph nodes in liver and gastrointestinal space, it is necessary to go to regular hospitals for further examination, to clarify the cause of the disease under the guidance of professional physicians, and to give targeted treatment to avoid delaying the condition.