Grand mal seizures refer to generalized tonic clonic seizures, and the preferred drugs are carbamazepine and sodium valproate, which are more effective for secondary epilepsy and sodium valproate for primary epilepsy, as well as some second-line drugs such as oxcarbazepine, lamotrigine, levetiracetam, and topiramate, which can be used to treat grand mal seizures. In addition older antiepileptic drugs, phenobarbital and phenytoin sodium are also effective in the control of grand mal seizures. Petit mal seizures refer to aphasic seizures. Currently, ethosuximide is preferred for aphasic seizures and carbamazepine cannot be used, which can worsen aphasic seizures. Other second-line drugs can be chosen from lamotrigine. Sodium valproate is also effective in aphasic seizures for patients who cannot purchase ethosuximide and cannot tolerate lamotrigine.