The exact cause of restless legs syndrome is not clear; restless legs syndrome is categorized into primary and secondary, which have different causes. It may be caused by genetic factors, underlying diseases, medications, etc. Primary restless legs syndrome is considered to be genetically related. Primary restless legs syndrome is considered to be genetically related, and abnormal dopamine function in the brain can also lead to neurological sensorimotor disorders. Secondary restless legs syndrome is usually related to some chronic diseases, such as chronic renal failure, rheumatoid arthritis, iron deficiency anemia, etc. Long-term development or treatment of these diseases may affect the nervous system, which may involve the nerves in the legs. In addition for some special treatments, such as hemodialysis or the use of some special drugs can affect the nerve function and induce this disease. Restless Legs Syndrome should be identified and treated under the guidance of a specialized physician.