Waking up in the morning with a runny nose and sneezing may be due to inhalation of irritating gases, sharp changes in temperature and other physiological factors. Or consider that it is caused by allergic rhinitis, upper respiratory tract infection and other diseases. 1. Physiological factors: When inhaling irritating gases such as pollen, dust, animal dander, etc. early in the morning, the human body will expel the foreign matter through sneezing. Or when the temperature changes drastically, it will also stimulate the human body to sneeze, mostly accompanied by the symptoms of a runny nose, if not accompanied by other uncomfortable symptoms, it is a normal phenomenon. 2. Pathological factors (1) Allergic rhinitis: allergic rhinitis is caused by a combination of genetic and environmental factors. Patients may have symptoms such as itchy nose, paroxysmal sneezing, watery nasal discharge and nasal congestion when they get up in the morning. (2) Upper respiratory tract infection: Upper respiratory tract infection is mostly due to pathogen infection, sudden change of climate, low immunity and other factors. If patients do not take good measures to keep warm while sleeping, it may lead to patients inducing upper respiratory tract infections and symptoms such as sneezing, runny nose and coughing when they get up in the morning. There are many reasons that lead to running nose and sneezing when getting up in the morning, and it is recommended that patients go to a regular hospital to find out the cause of the disease and receive treatment.