Hepatitis B core and surface antibody positivity usually does not require treatment, but HBVDNA should be tested to rule out occult HBV (hepatitis B virus) infection. Hepatitis B core antibody positivity means that you have been infected with hepatitis B. It is not certain that the virus has cleared. Hepatitis B surface antibody positivity means that you are immune to the hepatitis B virus and are usually a recovered hepatitis B patient or a vaccinated hepatitis B patient. However, when the hepatitis B virus is occultly infected, the hepatitis B surface antigen is negative, but the serum or liver tissue will be positive for hepatitis B virus DNA, and the hepatitis B core antibody and surface antibody are positive. Treatment is usually not needed and hepatitis B DNA testing can be performed to rule out occult HBV infection. Hepatitis B core antibody and surface antibody positivity, you can go to the hospital in time, to clarify the cause of the disease for targeted treatment.