Most people with multiple sclerosis are disabled. Multiple sclerosis is an autoimmune-related disease, and environmental and genetic factors are also involved in its development. The main manifestations are limb weakness, sensory abnormalities, visual impairment and ataxia. Most of them are relapsing and remitting process, nowadays the symptoms can be relieved after timely diagnosis and drug treatment, and can reduce relapses and slow down the progress. A small number of patients with multiple sclerosis have no residual neurological symptoms and signs for more than ten years after the onset of the disease, but most of the patients have residual neurological dysfunction after each relapse, and as the disease progresses, the residual symptoms gradually increase, which may eventually lead to disability. Active treatment and rehabilitation exercises can slow down the process of disability in patients with multiple sclerosis.