Ear pain at night is mainly considered inflammatory factors, such as acute otitis externa, herpetic tympanitis, acute otitis media and other diseases. 1. Acute otitis externa: may be due to the skin damage in the external auditory canal, or ear into the water, ear digging and other triggers, in the night time to sleep on the ear localized pressure as well as inflammation under the stimulation, and caused by the night ear pain. 2. Herpetic tympanitis: it is a viral infection, which may be related to colds and acute upper respiratory tract infections, and needs to be treated with antiviral drugs. 3. Acute otitis media: the main symptoms include earache, fever, ear pus, etc. It is related to the Eustachian tube route or bloodstream route infection. The use of anti-infective drugs is standardized. During the daytime, due to distraction, may be able to tolerate minor pain, sleep at night, due to the vagus nerve excitation, more sensitive to pain, so often at night due to ear pain to see the emergency room more patients. If the symptoms of ear pain continue unrelieved at night while sleeping, it is recommended to go to the hospital in time and be treated under the guidance of a doctor.