Potassium deficiency with generalized weakness and inability to stand up needs to be supplemented as soon as possible, and it is necessary to go to the hospital in time to clarify the cause of the disease and treat it aggressively. Common symptoms of hyperkalemia are muscle weakness and episodes of flaccid paralysis, which usually occur at night and after exertion, and the affected muscles are most common in the limbs. Hyperkalemia needs to be treated as soon as possible, otherwise it is prone to serious adverse effects such as cardiac arrhythmia and dyspnea. Oral or intravenous potassium supplementation needs to be administered under close monitoring. In addition to potassium supplementation, the etiology of hypokalemia needs to be clarified, such as severe diarrhea and vomiting, alkalosis, use of hydrochlorothiazide diuretics and other causes, which need to be treated according to the etiology. Potassium deficiency, generalized weakness and inability to stand up, should be promptly consulted and treated according to medical advice.